Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
| Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
| Upregulated in class | absentNotch |
| GeneSet | BIOCARTA_SKELETAL MUSCLE HYPERTROPHY IS REGULATED VIA AKT-MTOR PATHWAY |
| Enrichment Score (ES) | -0.7739623 |
| Normalized Enrichment Score (NES) | -1.5266771 |
| Nominal p-value | 0.008403362 |
| FDR q-value | 0.3088194 |
| FWER p-Value | 0.981 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RPS6 | 2060168 | 1114 | 0.426 | -0.0129 | No | ||
| 2 | EIF2B5 | 430315 6900400 | 1192 | 0.403 | 0.0274 | No | ||
| 3 | FRAP1 | 2850037 6660010 | 4045 | 0.055 | -0.1199 | No | ||
| 4 | PIK3R1 | 4730671 | 8693 | 0.005 | -0.3693 | No | ||
| 5 | MKNK1 | 6510161 | 11134 | -0.001 | -0.5004 | No | ||
| 6 | AKT1 | 5290746 | 11232 | -0.001 | -0.5054 | No | ||
| 7 | EIF2S1 | 5360292 | 11844 | -0.003 | -0.5380 | No | ||
| 8 | PIK3CA | 6220129 | 12641 | -0.006 | -0.5801 | No | ||
| 9 | IGF1R | 3360494 | 12883 | -0.007 | -0.5923 | No | ||
| 10 | EIF4EBP1 | 60132 5720148 | 13473 | -0.010 | -0.6228 | No | ||
| 11 | RPS6KB1 | 1450427 5080110 6200563 | 13918 | -0.015 | -0.6450 | No | ||
| 12 | EIF4E | 1580403 70133 6380215 | 14918 | -0.039 | -0.6944 | No | ||
| 13 | PDK2 | 2690017 | 15046 | -0.046 | -0.6962 | No | ||
| 14 | IGF1 | 1990193 3130377 3290280 | 15490 | -0.071 | -0.7122 | No | ||
| 15 | PTEN | 3390064 | 16640 | -0.215 | -0.7502 | Yes | ||
| 16 | INPPL1 | 110717 3120164 | 16896 | -0.274 | -0.7336 | Yes | ||
| 17 | PPP2R5D | 4010156 380408 5550112 5670162 | 17331 | -0.396 | -0.7133 | Yes | ||
| 18 | GSK3B | 5360348 | 17444 | -0.435 | -0.6713 | Yes | ||
| 19 | EIF4G1 | 4070446 | 17543 | -0.470 | -0.6246 | Yes | ||
| 20 | PDPK1 | 6650168 | 17599 | -0.496 | -0.5728 | Yes | ||
| 21 | EIF2S2 | 770095 2810487 | 17749 | -0.556 | -0.5195 | Yes | ||
| 22 | EIF4A1 | 1990341 2810300 | 18156 | -0.798 | -0.4532 | Yes | ||
| 23 | PABPC1 | 2650180 2690253 6020632 1990270 | 18558 | -1.760 | -0.2805 | Yes | ||
| 24 | PSMC4 | 580050 1580025 | 18600 | -2.570 | 0.0009 | Yes |
